出版物
2018
1: Peng X, Xu X, Wang Y, Hawke DH, Yu S, Han L, Zhou Z, Mojumdar K, Jeong KJ, Labrie M, Tsang YH, Zhang M, Lu Y, Hwu P, Scott KL, Liang H, Mills GB。A-to-I RNA编辑有助于癌症的蛋白质组学多样性。2018年4月23日。pii: s1535 - 6108(18) 30131 - 4。doi: 10.1016 / j.ccell.2018.03.026。[Epub ahead of print] PubMed pid: 29706454。
2:李杰,刘r,李茹,王y,棕褐色,李xj,钱x,张c,夏y,徐d,郭某,丁z,du l,zheng y,chen q,lorenzi pl,轧机GB,江T,Lu Z.Egfr-磷酸化血小板同种型磷酸溶酶1促进了PI3K活化。Mol细胞。2018年4月19日; 70(2):197-210.E7。DOI:10.1016 / J.MOLCE.2018.03.018。PubMed Pmid:29677490。
3: Khong H, Volmari A, Sharma M, Dai Z, Imo CS, hailmichael Y, Singh M, Moore DT, Xiao Z, Huang XF, Horvath TD, Hawke DH, Overwijk WW肽疫苗配方控制抗原提呈时间和肿瘤特异性CD8(+) T细胞应答的大小。J Immunol. 2018年5月15日;200(10):3464-3474。doi: 10.4049 / jimmunol.1700467。2018年4月11日。PubMed PMID: 29643190;PubMed Central PMCID: PMC5940548。
4: Peng X, Chen Z, Farshidfar F, Xu X, Lorenzi PL, Wang Y, Cheng F, Tan L, Mojumdar K, Du D, Ge Z, Li J, Thomas GV, Birsoy K, Liu L, Zhang H, Zhao Z, Marchand C, Weinstein JN;癌症基因组图谱研究网络,人类癌症代谢表达188bet体育网址亚型的分子特征和临床相关性。Cell rep 2018 Apr 3;23(1):255-269.e4。doi: 10.1016 / j.celrep.2018.03.077。PubMed PMID: 29617665;PubMed Central PMCID: PMC5916795。
5:钱X,Li X,Tan L,Lee JH,夏Y,Cai Q,Zheng Y,Wang H,Lorenzi Pl,Lu Z.MR Z.通过AMPK介导的磷酸化转化对单体的转化抑制核苷酸合成响应能量响应核苷酸合成压力。2018年1月;8(1):94-107。doi: 10.1158 / 2159 - 8290. - cd - 17 - 0712。EPUB 2017年10月26日。PUBMED PMID:29074724;PubMed Central PMCID: PMC5760453。
6:霍尔维特TD,Dagan S,Lorenzi Pl,Hawke DH,Scaraffia Py。位置稳定同位素跟踪器分析显示AEDES AEGYPTI蚊子氨代谢期间的碳途径。Faseb J. 2018 Jan; 32(1):466-477。DOI:10.1096 / FJ.201700657R。EPUB 2017 SEP 25. PUBMED PMID:28970248;PubMed Central PMCID:PMC5731135。
2017
1:张p,他d,xu y,hou j,pan bf,王y,liu t,戴维斯厘米,ehli ea,tan l,周f,胡j,yu y,chen x,nguyen tm,rosen jm,Hawke DH,JI Z,Chen Y.基因组 - 宽鉴定和转化起始的差异分析。NAT Communce。2017年11月23日; 8(1):1749。DOI:10.1038 / s41467-017-01981-8。PubMed Pmid:29170441;PubMed Central PMCID:PMC5701008。
2:龚伙子,李伊,刘cj,xiang y,李c,ye y,张z,hawke dh,公园pk,刁l,putkey ja,yang l,guo ay,林c,汉l。一个泛小核仁RNA在人癌中的表达及临床相关性的癌症分析。细胞批准。2017年11月14日; 21(7):1968-1981。DOI:10.1016 / J.CELREP.2017.10.070。PubMed Pmid:29141226。
3:王,梁K,胡问,李P,歌J,杨Y,姚明J, Mangala LS,李C,杨W,公园PK,霍克DH,周J,周Y,夏W,挂MC,标志着小,Gallick通用电气、Lopez-Berestein G,弗洛雷斯,Sood AK,黄年代,余D,林杨L, C . JAK2-binding长非编码RNA促进乳腺癌脑转移。中国临床医学杂志。2017年12月1日;127(12):4498-4515。doi: 10.1172 / JCI91553。2017年11月13日。PubMed PMID: 29130936;PubMed Central PMCID: PMC5707156。
4:钱旭,李旭,谭磊,李建华,夏勇,蔡强,郑勇,王华,Lorenzi PL, Lu Z. PRPS六聚体转化为单体对能量胁迫下核苷酸合成的抑制作用。2018年1月;8(1):94-107。doi: 10.1158 / 2159 - 8290. - cd - 17 - 0712。EPUB 2017年10月26日。PUBMED PMID:29074724;PubMed Central PMCID: PMC5760453。
5:Horvath Td,Dagan S,Lorenzi Pl,Hawke DH,Scaraffia Py。位置稳定同位素跟踪器分析显示AEDES AEGYPTI蚊子氨代谢期间的碳途径。Faseb J. 2018 Jan; 32(1):466-477。DOI:10.1096 / FJ.201700657R。EPUB 2017 SEP 25. PUBMED PMID:28970248;PubMed Central PMCID:PMC5731135。
6:Federico L,Chong Z,Zhang D,McGroil Dj,赵W,济业KJ,Vellano CP,Ju Z,Gagea M,Liu S,Mitra S,Dennison JB,Lorenzi Pl,Cardnell R,Diaa L,Wang J,Lu Y,Byers La,Perou Cm,Lin Sy,Mills GB。乳腺癌精密药物的小鼠临床前同胞移植模型。SCI ADV。2017年4月19日; 3(4):E1600957。DOI:10.1126 / SCIADV.1600957。Ecollection 2017年4月份PubMed Pmid:28439535;PubMed Central PMCID:PMC5397135。
7:林,胡锦涛Q,李C、Z,马G,王C,李J, Y,姚明J, K,王,公园PK,标志着小,周Y,周J,挂MC,梁H,胡锦涛Z,沈H·霍克DH,汉族L,周Y,杨林C、L .链接lncRNA与PtdIns(3、4、5)P (3) hyperactivate AKT和AKT抑制剂带来阻力。细胞生物学杂志。2017年3月;19(3):238-251。doi: 10.1038 / ncb3473。2017年2月20日。PubMed PMID: 28218907;PubMed Central PMCID: PMC5332298。
8:李C,王年代,邢Z,林,梁K歌J,胡问,姚明J,陈Z,公园PK,霍克DH,周J,周Y,张年代,梁H,挂MC, Gallick通用电气、汉L, C,杨L . ROR1-HER3-lncRNA轴调节Hippo-YAP信号通路调节骨转移。Nat Cell biology . 2017 Feb;19(2):106-119。doi: 10.1038 / ncb3464。2017年1月23日。PubMed PMID: 28114269;PubMed Central PMCID: PMC5336186。
9: Long Y, Tsai WB, Wang D, Hawke DH, Savaraj N, Feun LG, Hung MC, Chen HH, Kuo MT. Argininosuccinate synthetase 1 (ASS1)是精氨酸和谷氨酰胺饥饿靶向治疗化疗敏感性的常见代谢标志物。癌症Lett. 2017 3月1日;388:54-63。doi: 10.1016 / j.canlet.2016.11.028。EPUB 2016 2016年11月30日。PubMed Pmid:27913198。
2016
1:长Y,Tsai WB,Wang D,Hawke DH,Savaraj N,Feun Lg,Hung Mc,Chen Hh,Kuo Mt。AginInosuccinate合成酶1(ASS1)是针对靶向精氨酸和谷氨酰胺 - 饥饿疗法的化学敏感性的常见代谢标记。癌症Lett. 2017 3月1日;388:54-63。doi: 10.1016 / j.canlet.2016.11.028。EPUB 2016 2016年11月30日。PubMed Pmid:27913198。
2:笹ai K, Katayama H, Hawke DH, Sen S.与Aurora-B染色体乘客蛋白复合物相比,Aurora-C与Survivin和cenp的相互作用揭示了共享和独特的特征。公共科学图书馆。2016年6月22日;11(6):e0157305。doi: 10.1371 / journal.pone.0157305。eCollection 2016。PubMed PMID: 27332895;PubMed Central PMCID: PMC4917241。
3:李旭,钱旭,彭丽霞,蒋勇,Hawke DH,郑勇,夏勇,李建华,Cote G,王华,王磊,钱钦,陆铮。Nat Cell biology . 2016 May 27;18(6):709。doi: 10.1038 / ncb3361。PubMed PMID: 27230532。
4:李旭,钱旭,彭丽霞,蒋勇,Hawke DH,郑勇,夏勇,李建华,Cote G, Wang H, Wang L, Qian CN, Lu Z.从酮己糖激酶c到酮己糖激酶A的剪接开关驱动肝癌的形成。细胞生物学杂志。2016年5月;18(5):561-71。doi: 10.1038 / ncb3338。2016年4月18日。勘误表:Nat Cell Biol. 2016 May 27;18(6):709。PubMed PMID: 27088854;PubMed Central PMCID: PMC4888794。
5:李晓霞,蒋勇,Meisenhelder J,杨伟,Hawke DH, Zheng Y, Xia Y, alape K, He J, Hunter T, Wang L, Lu Z.线粒体转位PGK1在肿瘤发生中的作用及其在糖酵解和TCA循环中的作用。中国海洋大学学报(自然科学版)。2016年3月3日;61(5):705-719。doi: 10.1016 / j.molcel.2016.02.009。PubMed PMID: 26942675;PubMed Central PMCID: PMC4888784。
6:Ishizawa J, K小岛,Chachad D, Ruvolo P, V Ruvolo, Jacamo RO, Borthakur G,μH,曾庆红Z,课程Y,艾伦我王Z,马W,李HC, Orlowski R, Sarbassov dos D, Lorenzi PL,黄X, Neelapu党卫军,麦克唐纳T,米兰达RN,王M, Kantarjian H, Konopleva M,戴维斯再保险公司通过对ONC201的非典型综合应激反应诱导ATF4在血液系统恶性肿瘤中引发p53独立的凋亡。Sci Signal. 2016 Feb 16;9(415):ra17。doi: 10.1126 / scisignal.aac4380。PubMed PMID: 26884599;PubMed Central PMC4815038。
7:Klionsky DJ,Abdelmohsen K,Abe A,Abedin MJ,Abeliovich H,Acevedo Arozena A,Adachi H,Adams Cm,Adams PD,Adeli K,Adhihetty PJ,Adler SG,Agam G,Agarwal R,Aghi Mk,Agnello M.,aguistinis p,aguilar pv,Aguirre-Ghiso J,Airoldi Em,Ait-Si-Ali S,Akematsu T,Akporiarye等,Al-Rubeai M,Albaiceta Gm,Albanese C,Albani D,Albert ML,Aldudo J,AlgülH那Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC Jr, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR Jr, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chowdhury K, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, Ciarcia R, Ciechomska IA, Ciriolo MR, Cirone M, Claerhout S, Clague MJ, Clària J, Clarke PG, Clarke R, Clementi E, Cleyrat C, Cnop M, Coccia EM, Cocco T, Codogno P, Coers J, Cohen EE, Colecchia D, Coletto L, Coll NS, Colucci-Guyon E, Comincini S, Condello M, Cook KL, Coombs GH, Cooper CD, Cooper JM, Coppens I, Corasaniti MT, Corazzari M, Corbalan R, Corcelle-Termeau E, Cordero MD, Corral-Ramos C, Corti O, Cossarizza A, Costelli P, Costes S, Cotman SL, Coto-Montes A, Cottet S, Couve E, Covey LR, Cowart LA, Cox JS, Coxon FP, Coyne CB, Cragg MS, Craven RJ, Crepaldi T, Crespo JL, Criollo A, Crippa V, Cruz MT, Cuervo AM, Cuezva JM, Cui T, Cutillas PR, Czaja MJ, Czyzyk-Krzeska MF, Dagda RK, Dahmen U, Dai C, Dai W, Dai Y, Dalby KN, Dalla Valle L, Dalmasso G, D'Amelio M, Damme M, Darfeuille-Michaud A, Dargemont C, Darley-Usmar VM, Dasarathy S, Dasgupta B, Dash S, Dass CR, Davey HM, Davids LM, Dávila D, Davis RJ, Dawson TM, Dawson VL, Daza P, de Belleroche J, de Figueiredo P, de Figueiredo RC, de la Fuente J, De Martino L, De Matteis A, De Meyer GR, De Milito A, De Santi M, de Souza W, De Tata V, De Zio D, Debnath J, Dechant R, Decuypere JP, Deegan S, Dehay B, Del Bello B, Del Re DP, Delage-Mourroux R, Delbridge LM, Deldicque L, Delorme-Axford E, Deng Y, Dengjel J, Denizot M, Dent P, Der CJ, Deretic V, Derrien B, Deutsch E, Devarenne TP, Devenish RJ, Di Bartolomeo S, Di Daniele N, Di Domenico F, Di Nardo A, Di Paola S, Di Pietro A, Di Renzo L, DiAntonio A, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dickey CA, Dickson RC, Diederich M, Digard P, Dikic I, Dinesh-Kumar SP, Ding C, Ding WX, Ding Z, Dini L, Distler JH, Diwan A, Djavaheri-Mergny M, Dmytruk K, Dobson RC, Doetsch V, Dokladny K, Dokudovskaya S, Donadelli M, Dong XC, Dong X, Dong Z, Donohue TM Jr, Doran KS, D'Orazi G, Dorn GW 2nd, Dosenko V, Dridi S, Drucker L, Du J, Du LL, Du L, du Toit A, Dua P, Duan L, Duann P, Dubey VK, Duchen MR, Duchosal MA, Duez H, Dugail I, Dumit VI, Duncan MC, Dunlop EA, Dunn WA Jr, Dupont N, Dupuis L, Durán RV, Durcan TM, Duvezin-Caubet S, Duvvuri U, Eapen V, Ebrahimi-Fakhari D, Echard A, Eckhart L, Edelstein CL, Edinger AL, Eichinger L, Eisenberg T, Eisenberg-Lerner A, Eissa NT, El-Deiry WS, El-Khoury V, Elazar Z, Eldar-Finkelman H, Elliott CJ, Emanuele E, Emmenegger U, Engedal N, Engelbrecht AM, Engelender S, Enserink JM, Erdmann R, Erenpreisa J, Eri R, Eriksen JL, Erman A, Escalante R, Eskelinen EL, Espert L, Esteban-Martínez L, Evans TJ, Fabri M, Fabrias G, Fabrizi C, Facchiano A, Færgeman NJ, Faggioni A, Fairlie WD, Fan C, Fan D, Fan J, Fang S, Fanto M, Fanzani A, Farkas T, Faure M, Favier FB, Fearnhead H, Federici M, Fei E, Felizardo TC, Feng H, Feng Y, Feng Y, Ferguson TA, Fernández ÁF, Fernandez-Barrena MG, Fernandez-Checa JC, Fernández-López A, Fernandez-Zapico ME, Feron O, Ferraro E, Ferreira-Halder CV, Fesus L, Feuer R, Fiesel FC, Filippi-Chiela EC, Filomeni G, Fimia GM, Fingert JH, Finkbeiner S, Finkel T, Fiorito F, Fisher PB, Flajolet M, Flamigni F, Florey O, Florio S, Floto RA, Folini M, Follo C, Fon EA, Fornai F, Fortunato F, Fraldi A, Franco R, Francois A, François A, Frankel LB, Fraser ID, Frey N, Freyssenet DG, Frezza C, Friedman SL, Frigo DE, Fu D, Fuentes JM, Fueyo J, Fujitani Y, Fujiwara Y, Fujiya M, Fukuda M, Fulda S, Fusco C, Gabryel B, Gaestel M, Gailly P, Gajewska M, Galadari S, Galili G, Galindo I, Galindo MF, Galliciotti G, Galluzzi L, Galluzzi L, Galy V, Gammoh N, Gandy S, Ganesan AK, Ganesan S, Ganley IG, Gannagé M, Gao FB, Gao F, Gao JX, García Nannig L, García Véscovi E, Garcia-Macía M, Garcia-Ruiz C, Garg AD, Garg PK, Gargini R, Gassen NC, Gatica D, Gatti E, Gavard J, Gavathiotis E, Ge L, Ge P, Ge S, Gean PW, Gelmetti V, Genazzani AA, Geng J, Genschik P, Gerner L, Gestwicki JE, Gewirtz DA, Ghavami S, Ghigo E, Ghosh D, Giammarioli AM, Giampieri F, Giampietri C, Giatromanolaki A, Gibbings DJ, Gibellini L, Gibson SB, Ginet V, Giordano A, Giorgini F, Giovannetti E, Girardin SE, Gispert S, Giuliano S, Gladson CL, Glavic A, 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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016;12(1):1-222. doi: 10.1080/15548627.2015.1100356. Erratum in: Autophagy. 2016;12(2):443. Selliez, Iban [corrected to Seiliez, Iban]. PubMed PMID: 26799652; PubMed Central PMCID: PMC4835977.
8:林、李C、Z,胡问,梁K,汉族L, C,霍克DH,王,张Y, Y,马G,公园PK,周J,周Y, Z,周Y,标志着小,梁H,挂MC,杨林C、L .链接lncRNA激活常氧HIF1α信号在三阴性乳腺癌。细胞生物学杂志。2016年2月;18(2):213-24。doi: 10.1038 / ncb3295。2016年1月11日。PubMed PMID: 26751287;PubMed Central PMCID: PMC4791069。
9:Nika H,Angeletti Rh,Hawke DH。通过共价色谱法在逆相载体上固相衍生化后通过共价色谱法进行磷酸富集。方法Mol Biol。2016; 1355:31-50。DOI:10.1007 / 978-1-4939-3049-4_3。PubMed Pmid:26584917。
10: Thomas D. Horvath等用三重四极杆和轨道rap级质谱仪进行代谢物定量的比较。2016。第64届美国质谱学学会论文集。下载
2015
1: Lee YC, Lin SC, Yu G, Cheng CJ, Liu B, Liu HC, Hawke DH, Parikh NU, Varkaris A, Corn P, Logothetis C, Satcher RL, Yu-Lee LY, Gallick GE, Lin SH. bone derived Factors conferennovo Therapeutic Resistance in Metastatic Prostate Cancer(转移性前列腺癌)2015年11月15日;75(22):4949-59。doi: 10.1158 / 0008 - 5472. - 15 - 1215。2015年11月3日PubMed PMID: 26530902;PubMed Central PMCID: PMC4651787。
2: Zheng Y, Li X, Qian X, Wang Y, Lee JH, Xia Y, Hawke DH, Zhang G, lyj, Lu Z. secretand O-GlcNAcylated MIF结合人EGF受体并抑制其激活。细胞生物学杂志。2015 10月;17(10):1348-55。doi: 10.1038 / ncb3222。2015年8月17日。PubMed PMID: 26280537;PubMed Central PMCID: PMC4785887。
3:张LW, Walkiewicz KW, Besong TM, Guo H, Hawke DH, Arold ST, Mills GB。通过p85α单体-同型二聚体平衡调节PI3K通路。2015年7月29日;4:e06866。doi: 10.7554 / eLife.06866。PubMed PMID: 26222500;PubMed Central PMCID: PMC4518712。
4: Anishkin A, Vanegas JM, Rogers DM, Lorenzi PL, Chan WK, Purwaha P, Weinstein JN, Sukharev S, Rempe SB. Catalytic Role of the Substrate define Specificity of Therapeutic l-天冬酰胺酶。中华医学杂志。2015年8月28日;427(17):2867-85。doi: 10.1016 / j.jmb.2015.06.017。2015年7月2日。PubMed PMID: 26142822。
5:Miyake T,Pradeep S,Wu Sy,Rupaimoole R,Zand B,Wen Y,Gharpure Km,Nagaraja As,Hu W,Cho Ms,Dalton Hj,Previs Ra,Taylor Ml,Hisamatsu T,Kang Y,Liu T,Shacham S,McCauley D,Hawke DH,Wiktorowicz Je,Coleman RL,Sood Ak。XPO1 / CRM1抑制导致EIF5A的线粒体积累导致抗肿瘤效应。临床癌症Res。2015年7月15日; 21(14):3286-97。DOI:10.1158 / 1078-0432.ccr-14-1953。EPUB 2015年4月15日。PubMed Pmid:25878333;PubMed Central PMCID:PMC4506247。
6: Pasqualini R,米利根再保险,克里斯蒂安森博士,Cardo-Vila M, Driessen WH,佐丹奴RJ, Hajitou,黄平君AG)温家宝年代,Barnhart KF, Baze WB, Marcott VD,霍克DH KA, Navone NM, Efstathiou E, Troncoso P,洛布RR, Logothetis CJ,例如w .针对interleukin-11受体α在转移性前列腺癌:第一次作用于人体的研究。2015年7月15日;121(14):2411-21。doi: 10.1002 / cncr.29344。2015年4月1日。PubMed PMID: 25832466;PubMed Central PMCID: PMC4490036。
7:李X,王W,王J,Malovannaya A,Xi Y,Li W,Guerra R,Hawke DH,Qin J,Chen J.蛋白质组学分析揭示了不同的染色质相关和可溶性转录因子复合物。MOL SYST BIOL。2015年1月21日; 11(1):775。DOI:10.15252 / MSB.20145504。PubMed Pmid:25609649;PubMed Central PMCID:PMC4332150。
2014
1:张Chaluvally-Raghavan P, F, Pradeep年代,汉密尔顿MP,赵X, Rupaimoole R,苔藓T,陆Y, Yu年代,Pecot简历,Aure先生,Peuget年代,Rodriguez-Aguayo C,韩寒高清,张D, Venkatanarayan, Krohn M, Kristensen VN, Gagea M Ram P,刘W, Lopez-Berestein G, Lorenzi PL, Børresen-Dale,下巴K,灰色J, Dusetti新泽西,McGuire,弗洛雷斯,Sood AK,米尔斯GB。hsa-miR-569在3q26.2位点的拷贝数增加导致TP53INP1的丢失和上皮癌的侵袭性。中国癌症杂志。2014年12月8日;26(6):863-879。doi: 10.1016 / j.ccell.2014.10.010。PubMed PMID: 25490449;PubMed Central PMCID: PMC4261159。
2: heemann ML, Ilmer M, Silva LP, Hawke DH, Recio A, Vorontsova MA, Alt E, Vykoukal J. Benchtop分离和序列过滤功能外体的特性。J Chromatogr A. 2014 Dec 5;1371:125-35。PubMed PMID: 25458527。
3:邢Z,林A,李C,梁克,王思,刘y,公园PK,秦立,魏y,洪Mc,林C,杨L. lncrna指示趋化因子下游的协同表观遗传调控。细胞。2014年11月20日; 159(5):1110-1125。DOI:10.1016 / J.Cell.2014.10.013。EPUB 2014年11月13日。PubMed Pmid:25416949;PubMed Central PMCID:PMC4266991。
4: Jiang Y, Wang Y, Wang T, Hawke DH, Zheng Y, Li X, Zhou Q, Majumder S, Bi E, Liu DX, Huang S, Lu Z. PKM2磷酸化MLC2并调节肿瘤细胞分裂。Nat Commun. 2014 Nov 21;5:5566。doi: 10.1038 / ncomms6566。PubMed PMID: 25412762;PubMed Central PMCID: PMC4259466。
5:张LW, Yu S, Zhang D, Li J, Ng PK, Panupinthu N, Mitra S, Ju Z, Yu Q, Liang H, Hawke DH, Lu Y, Broaddus RR, Mills GB。自然发生的新形态PIK3R1突变激活MAPK通路,决定对MAPK通路抑制剂的治疗反应。2014 10月13日;26(4):479-94。doi: 10.1016 / j.ccell.2014.08.017。2014年10月2日PubMed PMID: 25284480;PubMed Central PMCID: PMC4198486。
Nika H, Angeletti RH, Hawke DH。n端蛋白的质谱分析,使用微尺度液相和固相衍生。生物技术学报。2014 9月;25(3):77-86。doi: 10.7171 / jbt.14 - 2503 - 001。PubMed PMID: 25187758;PubMed Central PMCID: PMC4136438。
7:Purwaha P,Lorenzi Pl,Silva LP,Hawke DH,Weinstein JN。鉴定对粘附细胞L-天冬酰胺酶的氨基酸响应的靶向代谢分析。代谢组学。2014; 10(5):909-919。EPUB 2014 2月7日PUBMED PMID:25177232;PubMed Central PMCID:PMC4145215。
8:Lorenzi Pl,Claerhout S,Mills GB,Weinstein JN。自噬调节蛋白质和小分子的策划人口普查:癌症治疗的候选目标。自噬。2014年7月10(7):1316-26。DOI:10.4161 / auto.28773。EPUB 2014 5月12日。PUBMED PMID:24906121;PubMed Central PMCID:PMC4203555。
9:Purwaha P,Silva LP,Hawke DH,Weinstein Jn,Lorenzi PL。LC-MS / MS测量中的谷氨酰胺和谷氨酸MS测量的伪影:在焦蛋白酸的源极环化。肛门化学。2014年6月17日; 86(12):5633-7。DOI:10.1021 / AC501451V。EPUB 2014年6月5日PUBMED PMID:24892977;PubMed Central PMCID:PMC4063328。
10:Nika H,Hawke DH,Angeletti Rh。用组合微级液体和固相衍生化氰基裂解后质谱法的N-末端蛋白表征。J Biomol Tech。2014年4月25日(1):19-30。DOI:10.7171 / JBT.14-2501-003。PubMed Pmid:24688320;PubMed Central PMCID:PMC3942260。
Nika H, Hawke DH, Angeletti RH质谱法鉴定c端蛋白:从溴化氰裂解蛋白中分离c端片段。生物技术学报。2014年4月;25(1):1-18。doi: 10.7171 / jbt.14 - 2501 - 001。PubMed PMID: 24688319;PubMed Central PMCID: PMC3942263。
12: Chan WK, Lorenzi PL, Anishkin A, Purwaha P, Rogers DM, Sukharev S, Rempe SB, Weinstein JNl -天冬酰胺酶的谷氨酰胺酶活性对asns阴性细胞的抗癌活性不是必需的。血液。2014年6月5日;123(23):3596-606。doi: 10.1182 /血液- 2013 - 10 - 535112。2014年3月21日。PubMed PMID: 24659632;PubMed Central PMCID: PMC4047499。
13:Kruger S,ABD Elmageed Zy,Hawke DH,WörnerPM,Jansen Da,Abdel-Mageed AB,Alt Eu,Izadpanah R.来自乳腺癌细胞的外渗囊泡的分子表征。BMC癌症。2014年1月27日; 14:44。DOI:10.1186 / 1471-2407-14-44。PubMed Pmid:24468161;PubMed Central PMCID:PMC3936808。
14:姜瑜,李晓霞,杨伟,Hawke DH,郑勇,夏勇,alape K,魏超,郭芳,陈勇,陆铮。PKM2调节肿瘤细胞染色体分离和有丝分裂进程。中国生物医学工程学报。2014 1月9日;53(1):75-87doi: 10.1016 / j.molcel.2013.11.001。2013年12月5日。PubMed PMID: 24316223;PubMed Central PMCID: PMC3955203。
2013
1:姜瑜,李旭,杨伟,Hawke DH,郑勇,夏勇,alape K,魏超,郭芳,陈勇,陆志强。PKM2调控肿瘤细胞染色体分离和有丝分裂进程。中国生物医学工程学报。2014 1月9日;53(1):75-87doi: 10.1016 / j.molcel.2013.11.001。2013年12月5日。PubMed PMID: 24316223;PubMed Central PMCID: PMC3955203。
第2集:温斯坦JN,洛伦兹PL.癌症:药物敏感性的差异。自然科学。2013年12月19日;504(7480):381-3。doi: 10.1038 / nature12839。2013年11月27日。PubMed PMID: 24284624。
3:庄聪,潘杰,Hawke DH,林舒,李玉丽。NudC去乙酰化调节有丝分裂进程。公共科学图书馆。2013 9月19日;8(9):e73841。doi: 10.1371 / journal.pone.0073841。eCollection 2013。PubMed PMID: 24069238;PubMed Central PMCID: PMC3777959。
4:Silva LP,Lorenzi Pl,Purwaha P,Yong V,Hawke DH,Weinstein JN。测量DNA浓度作为来自粘附细胞系代谢组数据的标准化策略。肛门化学。2013年10月15日; 85(20):9536-42。DOI:10.1021 / AC401559V。EPUB 2013年10月2. PUBMED PMID:24011029;PubMed Central PMCID:PMC3868625。
5:Nika H,Nieves E,Hawke DH,Angeletti Rh。通过共价色谱法在固定在反相载体上固定的蛋白质消化衍生后的磷酸肽富集。J Biomol Tech。2013年9月24日(3):154-77。DOI:10.7171 / JBT.13-2403-004。PubMed Pmid:23997662;PubMed Central PMCID:PMC3750845。
6: Nika H, Nieves E, Hawke DH, Angeletti RH优化β-消除/迈克尔加成化学反相载体上的质谱分析o连接蛋白修饰。生物技术学报,2013;24(3):132-53。doi: 10.7171 / jbt.13 - 2403 - 005。PubMed PMID: 23997661;PubMed Central PMCID: PMC3703673。
7: Nika H, Nieves E, Hawke DH, Angeletti RH微尺度液相和固相衍生联用质谱对c端蛋白的表征。生物技术学报,2013年4月;24(1):17-31。doi: 10.7171 / jbt.13 - 2401 - 003。PubMed PMID: 23543807;PubMed Central PMCID: PMC3518879。
8:卢j,ye x,粉丝f,xia l,bhattacharya r,bellister s,tozzi f,sceusi e,zhou y,tachibana i,maru dm,hawke dh,rak j,mani sa,zweidler-mckay p,ellisLM。内皮细胞通过可溶性形式的锯齿状-1促进结肠直肠癌干细胞表型。癌细胞。2013年2月11日; 23(2):171-85。DOI:10.1016 / J.CCR.2012.12.021。EPUB 2013年1月31日。PubMed Pmid:23375636;PubMed Central PMCID:PMC3574187。
9:Angelo LS,Maxwell DS,Wu Jy,Sun D,Hawke DH,McCutcheon IE,Slopis JM,Peng Z,Bornmann WG,Kurzrock R.姜黄素的姜黄蛋白在人类施瓦新笑细胞中染色伴侣:生物学意义。生物医学化学。2013 Feb 15;21(4):932-9。doi: 10.1016 / j.bmc.2012.12.008。EPUB 2012 DEC 13. PUBMED PMID:23294827。
2012
1: Angelo LS, Maxwell DS, Wu JY, Sun D, Hawke DH, McCutcheon IE, Slopis JM, Peng Z, Bornmann WG, Kurzrock R.人神经鞘瘤细胞中姜黄素的结合伙伴:生物学意义。生物医学化学。2013 Feb 15;21(4):932-9。doi: 10.1016 / j.bmc.2012.12.008。EPUB 2012 DEC 13. PUBMED PMID:23294827。
2:尼卡H,Lee J,Willis Im,Angeletti Rh,Hawke DH。用逆相载体用质谱法表征用于固相β-消除/迈克尔的逆相载体。J Biomol Tech。2012年7月23日(2):51-68。DOI:10.7171 / JBT.2012-2302-002。PubMed Pmid:22951960;PubMed Central PMCID:PMC3324170。
3: Dufour E, Gay F, Aguera K, Scoazec JY, Horand F, Lorenzi PL, Godfrin Y.胰腺肿瘤对血浆l -天冬酰胺饥饿的敏感性。胰腺。2012年8月,41(6):940 - 8。doi: 10.1097 / MPA.0b013e318247d903。PubMed PMID: 22513289。
2011
1: Tao RH, Berkova Z, Wise JF, Rezaeian AH, Daniluk U, Ao X, Hawke DH, Karp JE, Lin HK, Molldrem JJ, Samaniego F. PMLRARα结合Fas并通过招募c-FLIP抑制Fas介导的细胞凋亡。血液。2011年9月15日;118(11):3107-18。doi: 10.1182 / - 2011 - 04 - 349670血。2011年7月29日。PubMed PMID: 21803845;PubMed Central PMCID: PMC3291494。
2: Friedman DB, Andacht TM, Bunger MK, Chien AS, Hawke DH, Krijgsveld J, Lane WS, Lilley KS, MacCoss MJ, Moritz RL, settale RE, Sherman NE, Weintraub ST, Witkowska HE, Yates NA, Turck CW英国皇家空军蛋白质组学研究小组研究:蛋白188bet体育网址质组定性和定量分析的教育练习。蛋白质组学,2011年4月,11(8):1371 - 81。doi: 10.1002 / pmic.201000736。2011年3月11日。PubMed PMID: 21394914。
3: Claerhout S, Lorenzi PL, Weinstein JN, Mills GB自噬的调节及其在癌症治疗中的潜力。药物的未来。2011;36(12)。doi: 10.1358 / dof.2011.036.12.1711892。PubMed PMID: 25419038;PubMed Central PMCID: PMC4239665。
2010
1: Jin Q, Yuan LX, Boulbes D, Baek JM, Wang YN, Gomez-Cabello D, Hawke DH, Yeung SC, Lee MH, Hortobagyi GN, Hung MC, Esteva FJ脂肪酸合酶磷酸化:her2过表达乳腺癌细胞的新治疗靶点。6(6): 917。doi: 10.1186 / bcr2777。Epub 2010 11月16日。PubMed PMID: 21080941;PubMed Central PMCID: PMC3046439。
2:Giordano RJ,Cardó-Vila M,Salameh A,Anobom CD,Zeitlin BD,Hawke DH,Valente Ap,Almeida Fc,Nörje,锡德曼RL,Pasqualini R,ARAP W.从组合肽选择到药物原型(I):靶向血管内皮生长因子受体途径。Proc Natl Acad Sci U S A. 2010年3月16日; 107(11):5112-7。DOI:10.1073 / PNAS.0915141107。EPUB 2010 2月26日。PubMed Pmid:20190181;PubMed Central PMCID:PMC2841949。
3:Chen Ls,Du-Cuny L,Vethantham V,Hawke DH,Manley JL,张S,Gandhi V.通过改性ATP类似物的链终止和抑制哺乳动物聚(A)聚合酶。Biochem pharmacol。2010年3月1; 79(5):669-77。DOI:10.1016 / J.BCP.2009.09.028。EPUB 2009 OCT 6. PUBMED PMID:19814999;PubMed Central PMCID:PMC2812641。
2009
1:Chen Ls,Du-Cuny L,Vethantham V,Hawke DH,Manley JL,张S,Gandhi V.通过改性ATP类似物的链终止和抑制哺乳动物聚(A)聚合酶。Biochem pharmacol。2010年3月1; 79(5):669-77。DOI:10.1016 / J.BCP.2009.09.028。EPUB 2009 OCT 6. PUBMED PMID:19814999;PubMed Central PMCID:PMC2812641。
2:Jobson AG,Lountos GT,Lorenzi Pl,Llamas J,Connelly J,Cerna D,Tropea Je,Onda A,Zoppoli G,Kondapaks,Zhang G,Caplen NJ,Cardellina JH 2,Yoo SS,僧侣A,Self C那Waugh DS, Shoemaker RH, Pommier Y. Cellular inhibition of checkpoint kinase 2 (Chk2) and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019 [7-nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide]. J Pharmacol Exp Ther. 2009 Dec;331(3):816-26. doi: 10.1124/jpet.109.154997. Epub 2009 Sep 9. PubMed PMID: 19741151; PubMed Central PMCID: PMC2784710.
3:Lorenzi PL,Reinholt Wc,Varma S,Hutchinson AA,Pommier Y,Chanock SJ,Weinstein JN。NCI-60细胞系面板的DNA指纹纹理。莫癌。2009年4月8日(4):713-24。DOI:10.1158 / 1535-7163.mct-08-0921。PubMed Pmid:19372543;PubMed Central PMCID:PMC4020356。
4:Lorenzi Pl,Weinstein JN。天冬酰胺合成酶:卵巢癌中的新潜在生物标志物。药物新闻持态度。2009年1月至2月; 22(1):61-4。DOI:10.1358 / DNP.2009.22.1.1303820。审查。PubMed Pmid:19209300;PubMed Central PMCID:PMC4096155。