当氧气短时，EGFR阻止癌症 - 战斗机械

在肿瘤经常遇到的氧气饥饿条件下，癌症促进表皮生长因子受体（EGFR）牙龈上调细胞的肿瘤抑制microRNA（miRNA） - 由MD Anderson科学家领导的国际团队发现。

“当缺氧强调细胞时，EGFR信号传导可防止未成熟的miRNA成长以生长癌症，”高级作者说Mien-Chie Hung，Ph.D。，教授和主席分子和细胞肿瘤学露丝Legett Jones尊敬的椅子的持有人。

本集团的发现指向潜在的新预后标志物乳腺癌，挂笔记，还提供了调节miRNA成熟的生长因子信号通路的第一种证据。

This research was funded by grants from the U.S. National Institutes of Health, MD Anderson’s Cancer Center Support Grant from the National Cancer Institute, the U.S. National Breast Cancer Foundation, MD Anderson’s Center for Biological Pathways, Susan G. Komen for the Cure, the Sister Institution Fund of China Medical University and Hospital and MD Anderson, the Taiwan Cancer Research Center of Excellence, a Private University grant from Taiwan and the Taiwan Program for Stem Cell and Regenerative Medicine Frontier Research.