血小板水平的高度升高促进了肿瘤的生长,降低了肿瘤的存活率卵巢癌患者报告MD安德森《新英格兰医学杂志》上发表了一篇文章。188bet体育网址
通过在一个百年历史的临床观察的核心定位一个强大的原因和效应关系,团队揭示了癌症进展和新潜在治疗方法的新因素。
“我们的合作研究不仅发现了解释血小板计数升高的机制,而且还将这种被称为血小板增多的状态与卵巢癌的严重程度联系起来,”资深作者说阿尼尔·苏德,医学博士。他是MD安德森大学的教授妇科、肿瘤科和生殖内科和癌症生物学。“这表明干扰凝血的药物可能是传统治疗的有用补充。”
Sood及其同事们从卵巢癌患者中吸引了临床资料,然后随访了小鼠模型实验和临床试验。
Funding for this research came from the Gynecologic Cancer Foundation’s Gail MacNeil KOH Research Award, the National Cancer Institute, a Program Project Development Grant from the Ovarian Cancer Research Fund, the U.S. Department of Defense, the Baylor College of Medicine and MD Anderson Cancer Center Multidisciplinary Research Program, the Anne and Henry Zarrow Foundation, the Marcus Foundation Inc., the estate of C.G. Johnson Jr., the United Kingdom Medical Research Council, the Blanton–Davis Ovarian Cancer Research Program, the Laura and John Arnold Foundation, the RGK Foundation and the Bettyann Asche Murray Distinguished Professorship in Ovarian Cancer Research.