Building on progress against pancreatic cancer

在全国范围内，人诊断出患有胰腺癌只有约9％的存活五年。在大多数情况下，这种疾病已经通过它的发现时间扩散到其他器官。

Surgery is the standard of care when the tumor is surgically removable, but even then the median survival for such patients is about 22 months.

在MD安德森，这43个月，对常规术前处理和成像，手术，放疗，化疗的稳步改善，并通过研究和临床试验多学科协同工作在过去的25年建成其他专业的转变的结果。188bet体育网址现在，MD安德森的胰腺癌月shot™影像adds analytical capabilities.

How to make surgery more successful

Less toxic chemotherapy combinations and targeted radiation before surgery can improve the prospects of patients whose tumors might once have gone to surgery first, saysRobert Wolff, M.D., professor of Gastrointestinal Medical Oncology, also a Moon Shot co-leader and Sheikh Zayed Bin Sultan Al Nahyan Distinguished University Chair in Medical Oncology.

Safer and more effective surgical techniques as well as improvements in care right before, during and after surgery have been critical in improving survival.

“我们在手术后90天内死亡率的患者基本上为0％，而我们的手术后住院天数为6天，”卡茨笔记。

在全国范围内，手术相关的致死率约为8％，而手术后住院超过10天。

手术前的治疗也被用来收缩更多的局部晚期肿瘤，使它们可移动，沃尔夫说。仔细的评估有助于确保疾病没有扩散到其他器官，因为手术是徒劳的，然后。

什么工作，为什么只是一些

Understanding why patients like Lusby do well and why treatment is less effective for others is central to improving results for patients with non-metastatic disease.

血液和肿瘤样本的深层分子分析会帮助球队解决这些问题。

“We aim to bring novel clinical trials to these patients and conduct correlative studies to understand factors involved in response to, or resistance to, treatment,” saysAnirban迈特拉，M.B.B.S., professor ofPathology中，谢赫·艾哈迈德·中心的胰腺癌研究的登月和导演的共同领导。188bet体育网址

通过登月，MD安德森专家正在寻找提高使用被称为立体定向放射治疗（SBRT）的缩写放射治疗胰腺癌的治疗。SBRT具有比常规放射相似或有时效果更好，但给予五天，而不是6周，允许短期停留的MD安德森外的小镇患者。该疗法可提供高剂量的辐射，使用旨在以不同的角度变化的强度的若干光束精确地靶向肿瘤。

This precise targeting of the tumor has less effect on surrounding organs, so there’s limited toxicity. Conventional radiation requires concurrent chemotherapy and can lead to more toxicity because it usually includes a larger volume of radiation over time. SBRT uses a smaller, more focused volume and therefore can be easier on patients’ immune systems.

Learn more about MD Anderson’s team approach to pancreatic cancer in征服杂志。