三项全能运动员和马拉松选手莱斯利·罗素教给孩子念故事与在春枝学区诵读困难。这是一个工作，她在她长大的社区爱。
年度报告2014：巨蟹座无法比拟的我们的决心
难道质子治疗是头部和颈部癌症治疗的“圣杯”？
The good news is death rates continue to decline for the most common types of cancer, including lung, colon, breast and prostate.
Steven Frank, medical director of MD Anderson’s Proton Therapy Center, is seeing success in treating oropharyngeal cancer patients with intensity modulated proton therapy. The approach spares healthy tissue surrounding the tumor and reduces side effects. Photo: Eric Kayne
The bad news is a far less common head and neck cancer is rising sharply. Since the late 1980s, cases of oropharyngeal cancers that attack the back of the throat, the base of the tongue and the tonsils have jumped 225%. According to the疾病预防与控制中心, almost three-fourths of the cases are linked to HPV, the human papillomavirus.
“Smoking and alcohol were the main causes of oropharyngeal cancers prior to this millenium, but HPV infections linked to the sexual revolution are now causing most of these cancers,” says Steven Frank, M.D., associate professor ofRadiation Oncology。
Even when diagnosed in late stage, most oropharyngeal cancers can be cured. But the radiation therapy traditionally used to treat head and neck cancers can cause debilitating side effects, including mouth and gum ulcers, difficulty swallowing, loss of appetite and the need for feeding tubes and hospitalization.
“Radiation destroys the cancerous cells,” Frank explains, “but it also destroys healthy cells, which can cause painful and difficult side effects.”
2010年,安德森的质子治疗中心,在哪儿e Frank serves as medical director, became the first site in North America to treat patients with intensity modulated proton therapy (IMPT). The technique uses an intricate network of magnets to aim a narrow proton beam at a tumor and “paint” the radiation dose onto it layer by layer. Healthy tissue surrounding the tumor is spared, and side effects are reduced.
A small but promising study conducted by
MD安德森
last year showed that oropharyngeal cancer patients treated with IMPT needed feeding tubes only half as often as patients treated with standard radiation therapy. The study also showed that toxicity levels were dramatically lower in IMPT patients compared to patients treated with standard therapy.
A second MD Anderson study treated 15 head and neck cancer patients with an advanced form of IMPT, known as multi-field optimization intensity modulated proton therapy (MFO-IMPT). The treatment maps the location, size and dimensions of hard-to-reach, complicated tumors, then sends a potent dose of protons to attack the tumors in the “nooks and crannies” of the head and neck or skull base where they live, says Frank, the lead investigator of both studies.
Two years and four months after the study concluded, 93% of participants remained cancer free. During treatment, all reported that side effects were greatly reduced, prompting some radiologists to label IMPT the “holy grail” for head and neck cancers.
With these promising findings, MD Anderson, in collaboration with马萨诸塞州总医院的弗朗西斯H.伯尔质子治疗中心，先后被授予从$ 20万美元的赠款National Institutes of Healthto further study the role of IMPT in the treatment of head and neck cancers. The first randomized study has been opened to patients, with additional trials expected later this year.
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Grants fuel tomorrow’s cancer breakthroughs
A state of Texas program designed to expedite innovations in new cancer treatments has helped MD Anderson recruit several new faculty members during the past year.
产业合作促进免疫系统的抗癌能力
MD安德森’s expertise in cancer immunotherapy attracted the interest of four major pharmaceutical companies, which signed three-year collaborative agreements in early 2014 to develop new ways for the immune system to destroy tumors.
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玛丽埃塔克莱因是一个忙碌的女人。作为一名医生，有四个子女，谁爱旅行和构建定制家具，她是个拼命三郎，很少有时间来备用。
交流计划带来最好的巴西
作为一个年轻人在圣保罗长大，迪奥戈Bugano迪尼兹戈麦斯被东西的工作原理，以及如何解决这些问题时，他们打破了着迷。
A call to action in South Texas
Since its introduction in the 1940s, the Pap test has been successfully detecting abnormal cells in the cervix that, if left untreated, could lead to cancer. In fact, that success has led to a 70% drop in cervical cancer rates in the United States.
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With elevated risks, these survivors and ‘previvors’ aren’t taking any chances
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解决婴儿潮一代与丙型肝炎问题
Baby boomers — Americans born between 1945 and 1965 — grew up in one of the wealthiest, most idealistic and physically fit generations in history.
推广提供了筛选和希望有需要的社区
More than 3,500 local women who are low income and uninsured have received free mammograms through an MD Anderson community outreach initiative.
A survivor is saving lives through early detection
It was 1980 when Janelle Hail of Frisco, Texas, discovered a small lump during a self-breast exam. A visit to the doctor resulted in an early breast cancer diagnosis. The then-34-year-old mother of three feared for her life. Today, she attributes her survival to early detection.
