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查看临床试验Pancreatic cancer occurs when cancer cells form and grow within the pancreas. These tumors are hard to diagnose early, since pancreatic cancer signs and symptoms aren’t obvious. Because of this, the majority of these cancers are diagnosed after the disease has reached an advanced stage, when treatment options are limited.
Pancreatic cancer occurs when cancer cells form and grow within the pancreas. These tumors are hard to diagnose early, since pancreatic cancer signs and symptoms aren’t obvious. Because of this, the majority of these cancers are diagnosed after the disease has reached an advanced stage, when treatment options are limited.
胰腺癌是美国癌症死亡的第四大原因。据估计,超过50000个新的病例每年诊断和超过40000人死于这种疾病每年。发生疾病的危险性为1.6%。风险是差不多的男女和年龄的典型范围在诊断时间是65〜74年岁之间。
关于胰腺
胰腺是位于胃的下部后面的长形元件,在胃和脊柱之间。它生产果汁,在帮助消化,并使胰岛素等激素的分泌,帮助人体吸收糖分和控制血糖。
胰腺主要包含两种细胞:
- 外分泌细胞,使与释放酶在食物的消化援助。
- Endocrine cells, which produce and release important hormones directly into the bloodstream.
大多数胰腺癌在该行胰腺导管外分泌细胞开始。这些被称为胰腺癌。
当癌细胞开始在胰腺内分泌细胞,它被称为pancreatic neuroendocrine tumor (NET)。有此类型的肿瘤的许多亚型。
This summary is about exocrine pancreatic cancer. Further mention of pancreatic cancer refers only to pancreatic adenocarcinoma, and not pancreatic NETs.
胰腺癌的危险因素
任何增加你患胰腺癌的几率是一个危险因素。有些危险因素是可以改变的,而有些则不能。
可以改变的危险因素包括:
- 吸烟和烟草的使用:People who smoke are about twice as likely to develop pancreatic cancer.
- 肥胖:作为非常超重(具有提高身体质量指数,或BMI)增加你20%,患胰腺癌的几率。
Other pancreatic cancer risk factors can’t be changed, including:
- Age:胰腺癌的风险大幅增加后55岁。
- 种族:非裔美国人更可能有胰腺癌比其他族群。
- 家史:遗传性基因的改变可能占胰腺癌的大约10%。遗传综合征,可引起外分泌胰腺癌的实例包括:遗传性乳腺癌,并在BRCA1或BRCA2基因突变引起的卵巢癌综合征,Lynch综合征(通常在MLH1或MSH 2个基因缺陷),和遗传性胰腺炎由于PRSSI基因突变。
- 糖尿病:与长期型的历史2型糖尿病的人,患胰腺癌的可能性增加。
- Chronic pancreatitis:胰腺的长期炎症与增加胰腺癌的发病率的联系,尤其是吸烟者。
不是每个人都与上述风险因素得到胰腺癌。但是,如果你有危险因素,应该与医生讨论他们。
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为什么选择MD安德森for pancreatic cancer treatment?
该病已到晚期,这让他们很难治疗后胰腺癌的约80%被确诊。小于当癌细胞仍局限在胰腺或接近周边地区胰腺癌的20%被发现。虽然这种疾病还没有扩散,这些情况与需要的经验,高水平的安全和有效地进行复杂的外科手术治疗。
Whether you’re diagnosed with localized or metastatic pancreatic cancer, it’s important to find a team of physicians with the most innovative treatment options and expertise. At MD Anderson, you are the focus of a personalized pancreatic cancer treatment plan that brings together a multidisciplinary team of some of the top pancreatic cancer professionals that use the most advanced techniques.
World-class surgeons treating localized pancreatic cancer
当胰腺癌局限在胰腺,有时当它只是传播到附近地区,它可以用手术切除。当肿瘤被完全去除治疗成功的几率最高的发生,以及所需要的手术技术是极其复杂的。因为我们的医生是最有经验和熟练的在全国前列,MD安德森has:
- The highest 5-year survival rate reported in the surgical literature for patients who have undergone surgery for pancreatic cancer.
- Less than a 1% mortality rate after surgery. That is over 6% lower than the national average.
- 在手术后住院时间最短平均长度。
Pioneers of pancreatic cancer treatment
我们的专家提供全面的胰腺癌护理,他们已经率先在该领域,包括一些进展:
- 在术前设置的使用化疗和/或辐射。
- Establishment of the “borderline resectable” staging subgroup and definition of the best course of treatment. Incorporating this staging group leads to larger numbers of patients with advanced cancer that may benefit from combining several types of therapy, including surgery.
- Innovative radiation techniques, such as giving higher-than-normal doses of radiation therapy (dose escalation) and stereotactic body radiation therapy (SBRT).
发展中国家通过临床试验更有效的治疗方案
MD安德森进行了广泛的临床试验to test new and innovative treatment options for both localized and metastatic pancreatic cancer. The treatment options used in these trials often cannot be found anywhere else and are critical for advancingpancreatic cancer treatment。
Current clinical trials focus on:
- 术前结合几种类型的疗法来治疗可切除及可能切除胰腺癌。
- 确定使用化疗和放疗治疗不能手术切除的胰腺癌肿瘤的更有效的方法。
- 开发已经转移的胰腺癌更有效的治疗方案。
- Detecting pancreatic cancer earlier (especially in patients with risk factors).
- Promoting healthy habits that enhance the effectiveness of treatment.
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提供最先进的放射治疗技术
放射治疗可以在胰腺癌治疗的有力工具。我们的放射肿瘤学家正处于专家体部立体定向放射治疗(SBRT)和dose-escalation, which allow high doses of radiation to be delivered to the tumor without damaging healthy tissue. ManyMD安德森faculty have led or are leading national clinical trials to improve radiation therapy for pancreatic cancer.
在MD安德森,我感到安全;我感到很自在;我觉得爱和照顾。
Diego Zamora
胰腺癌幸存者
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治疗在MD安德森
Pancreatic cancer treated in our Gastrointestinal Center.
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Prevention & Screening
Many cancers can be prevented with lifestyle changes and regular screening.
辅导服务
MD安德森已经获得社会工作者帮助患者和他们的亲人应对癌症。