MD安德森applauds FDA approval of HPV vaccine

MD安德森新闻Release December 11, 2014

MD安德森新闻Release 12/11/2014

The Food and Drug Administration’s (FDA)approval of a new vaccine that targets five additional strains of human papilloma virus (HPV)固本一个成熟的防癌的武器，根据罗纳德·A·迪皮诺，医学博士，总裁得克萨斯大学MD安德森癌症中心的大学。

The FDA greenlighted use of Gardasil 9 for the prevention of certain cancers caused by nine HPV strains – five more than its predecessor, Gardasil. The FDA said Gardasil 9 has the potential to prevent the vast majority of cervical, vulvar, vaginal and anal cancers.

“This is an incredible step forward in our fight to end cancer,” said DePinho. “Up to 80 percent of the world will be infected with HPV at some point, according to estimates. MD Anderson hopes the vaccine approval will change the conversation about HPV vaccination from sex to saving lives.”

儿童HPV疫苗接种已在导致今天的FDA宣布讨论的中心。DePinho，三个孩子的父亲，认为MD安德森可以帮助通过HPV疫苗保护儿童带路。他认为HPV疫苗“全国儿童福利的优先级和主要的父母责任。”

MD安德森clinicians and researchers are spearheading an institution-wide approach to addressing HPV-related cancers. Programs already are underway for parents, educators, clergy, policy makers and the general public to increase HPV vaccination rates in Texas and across the nation, improve early screening and detection and develop novel therapies.

MD安德森的优先事项包括努力提高甄别能力，并从实验室及时移动的生物医学研究成果到床边。188bet体育网址临床研究工作利用高188bet体育网址分辨率显微内窥镜（HRME），低成本的替代阴道镜检查及活检，可以证明在低资源环境尤为重要。一个社区宣传计划，以提高筛查和预防在得克萨斯州与墨西哥边境德州下里奥格兰德河谷将在子宫颈癌率高达30％，比全国平均水平的地区患者受益。

“此外，我们正在开发18个州与同行机构的全国合作伙伴关系，以增加HPV疫苗接种率，” DePinho说。“一个主动出资为150万$将导致一个无与伦比的努力，加速科学发现到临床进展的转换。”

According to Lois M. Ramondetta, M.D., associate professor, gynecologic oncology, this new vaccine will cover close to 90 percent of cervical cancers, one of the most common forms of cancer caused by HPV.

“If we can increase vaccination rates in this country, this vaccine approval has the power to save thousands of lives,” she said.

以下是有关在美国HPV相关癌症和免疫接种的事实：

•HPV感染占全世界所有癌症的5％ - 例包括子宫颈癌，口咽（头/颈），肛门，外阴，阴道和阴茎癌。

•本就占据了今年45000箱子预防癌症和10000人死亡，在美国。

• Oropharyngeal cancers affect men by a ratio of four-to-one and are on course to eclipse that of cervical cancer, the disease for which the vaccine was originally approved and marketed.

•预防和治疗HPV相关的癌症的年度直接医疗费用估计为$ 8十亿。

• Just 57 percent of girls and 35 percent of boys are estimated to be vaccinated, far short of the Healthy People 2020 goal of at least 80 percent of children vaccinated against HPV.

•只有三分之一的女生只有不到六个之一的孩子们收到的所有三个疫苗剂量。